Winning the game, whether here on on the TV show, depends on your intuition and luck.
Each number is random, including the monetary amount in the briefcases. Apart from that, there’s no strategy you have to bother with when it comes to playing Deal or No Deal Live. While the value of your briefcases is determined by your stake, you need to take the 95,42% RTP into account, so you should carefully consider how much to bet.